Patients with septic throat and high fever should be given antipyretic treatment and anti-infective treatment as follows: 1. Antipyretic treatment: antipyretic treatment should be given, that is, drugs are needed to reduce fever, you can choose ibuprofen, acetaminophen for antipyretic treatment, if it persists, you can also consider adding glucocorticoids, such as dexamethasone, methylprednisolone. 2. Anti-infective treatment: the specific cause should be clarified. If it is acute purulent tonsillitis, you need to actively give anti-infection treatment, choose antibiotics such as amoxicillin clavulanate potassium, piperacillin. If the pathogenic bacteria are not clear, you can also extract purulent secretions, culture and drug sensitivity test, according to the results of culture and drug sensitivity test, choose sensitive antibiotics, and finally to exclude whether the lower respiratory tract infection is complicated, you can improve blood analysis, chest X-ray, lung CT examination.