When the wall of the descending colon is slightly thickened and accompanied by inflammatory exudation, it is necessary to take anti-inflammatory drugs to carry out anti-inflammatory treatment, and can also be combined with the gastrointestinal mucosal protection agent to repair the intestinal mucosa. 1. Anti-inflammatory drugs: a slight thickening of the wall of the descending colon accompanied by inflammatory exudation, generally need to consider the inflammation of the colon, you can take anti-inflammatory drugs such as levofloxacin tablets or amoxicillin, to effectively get rid of the inflammation of the mucous membrane, thus helping to alleviate the symptoms of mucous membrane thickening, inflammation, hematoma and so on. 2. Mucosal protectant: Due to the slight thickening of the colon wall and the presence of inflammation, it will cause the gastrointestinal mucosa to have different degrees of damage. If left untreated, it may cause ulcers or bleeding. Therefore, appropriate administration of gastric mucosal protective agents such as aluminum magnesium sulfate chewable tablets or aluminum thioglycollate can help promote the recovery of the mucosal surface. After the thickening and inflammation of the descending colon or other digestive system, timely medication is needed, follow the doctor’s instructions to use medication cautiously, and usually the digestive tract can be protected by adjusting the diet.