The treatment of one eye big and one eye small needs to be decided according to the individual’s specific situation, if it is congenital generally do not need special treatment, if it is caused by acquired lesions, the feasibility of surgical treatment to correct. If the patient’s one eye is small because of congenital factors, without other clinical manifestations and discomfort, you can first observe, generally do not need to do special treatment. If the patient feels that it affects vision or aesthetics, consult a doctor for surgical treatment, such as eye opening surgery for smaller eyes. If the ptosis of one eye is caused by the ptosis of one eye, one eye is big and the other eye is small, then you need to go to the hospital in time, and after excluding other lesions, you can have a ptosis correction surgery to improve the condition. If the eyeball is protruding due to orbital tumors or intraocular space-occupying lesions that cause one eye to be large and the other small, then a detailed examination should be done first, and based on the results of the examination, the doctor should be consulted to perform a surgical treatment, such as surgical removal of the mass. It is recommended that patients with double eye size discrepancy should consult a doctor in time to evaluate their condition and follow the doctor’s instructions for treatment.