Whether cystatin C is 0.1mg/L above the upper limit of normal value is serious or not needs to be judged in combination with other indicators such as urine routine and renal function, and should not be generalized. If only cystatin C rises, urine routine and renal function tests are not abnormal, it may be a physiological phenomenon, such as when the patient drinks too little water to cause blood concentration, there may be a transient increase in this indicator, usually timely hydration and rest can be restored to normal, this time is not serious. If cystatin C level rises, accompanied by other abnormal renal function indicators such as increase in blood creatinine, it may reflect that the patient’s glomerular filtration rate has decreased and renal function is impaired, which is more serious and requires active treatment of the primary disease. If patients find that cystatin C is elevated, it is recommended that they go to a regular hospital in time, complete the examination to determine the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.