Observation】 1. Observe systemic symptoms such as anemia, fatigue, emaciation, night sweats, fever, itchy skin cancer, hepatosplenomegaly, etc. 2.Observe the scope and size of lymph node enlargement. 3. Closely observe whether there are any compression symptoms caused by deep lymph node enlargement, such as cough, respiratory difficulty and superior vena cava compression caused by mediastinal lymph node enlargement, and renal pelvic effusion caused by ureter compression caused by retroperitoneal lymph node enlargement. 4. Observe the presence of skeletal infiltration and be alert to the occurrence of pathological fracture and spinal cord compression. Symptomatic care】 1. Follow the fever care routine when the patient is febrile. 2. Give high-flow oxygen inhalation, semi-recumbent position, and appropriate amount of sedation in case of respiratory distress. 3.Reduce the activity when the bones are infiltrated, prevent trauma, and treat the pathological fracture according to the fracture site when it occurs. General care】 1. Early patients can be appropriately active, with fever and obvious infiltration symptoms should be bed rest to reduce consumption and protect the organism. 2. Give high-calorie, high-protein, vitamin-rich and easy-to-digest food and drink more water. To enhance the body’s tolerance to chemotherapy and radiotherapy, and promote the excretion of toxins. 3, keep the skin clean, scrub with warm water every day, especially to protect the skin of radiotherapy irradiation area, avoid all stimulating factors such as sunlight, hot and cold, various disinfectants, soap, adhesive tape and other stimulation of the skin, underwear use absorbent soft cotton fabrics, should be wide. 4, radiotherapy, chemotherapy should be observed when the treatment effect and adverse reactions. Health guidance] 1. Pay attention to personal hygiene, keep warm and prevent various infections. 2, strengthen nutrition, improve resistance. 3.Adhere to medical advice and regular follow-up.