Chest pain after waking up may be caused by the following conditions: 1. It may be caused by stomach discomfort, such as gastritis, gastric ulcer, duodenal ulcer and so on. The pain is usually located near the chest, under the fenestra, and is due to the long fasting time in the morning after waking up, the secretion of gastric acid in the body increases, stimulating local gastric lesions, resulting in local pain. 2, it may be some injury or inflammation of the soft tissues of the chest, for example, sometimes sleeping on the stomach, or by some heavy quilt or next to the sleeper’s 3.It may also be the pain caused by thoracic costochondritis, saberitis, or costochondritis.