The difference between cold knife conization of the cervix and Lipo knife is that cold knife conization will not damage the surface of the resected material, and it will be clearer when doing pathological examination to know whether the diseased tissue has been cut cleanly or not, while the Lipo knife is to resect the cervix through the thermal effect, which will make the diseased tissue necrotic around, and it will be difficult to find out whether there are still diseased cells at the edge of the resected cervical area when doing pathological examination. If the cervical epithelium has high-grade lesions, it is recommended to do cold knife conization of the cervix, which will be better and must be regularly reviewed after the operation.