Blisters are medically referred to as blisters. A lot of small blisters on the top of the hand may be caused by herpes sweat, tinea cruris, eczema on the hand, etc. Under the guidance of the doctor, you can relieve the symptoms by topical medication, oral medication and general treatment. 1. Sweat blisters: Sweat blisters can cause a lot of small blisters on the top of the hands, which may be caused by long-term exposure to ultraviolet rays or seasonal changes, and is accompanied by itching and a burning sensation. It can be treated by applying medicines such as glycerine lotion and tretinoin ointment under the guidance of a doctor. 2. ringworm: due to the hand skin is fungal infection caused by the hand above the long a lot of small blisters, may be in the unclean hygiene, the patient can be shared towels, gloves and other contact infections. Can be treated by topical miconazole nitrate ointment, clotrimazole ointment and other antifungal drugs, the effect of topical drugs is not good or extensive lesions can be combined with oral itraconazole and other drugs. 3. Hand eczema: Hand eczema is mainly caused by contact with irritating substances, such as detergents, soaps, etc., resulting in a lot of small blisters on the hands. Under the guidance of the doctor can be through the mometasone furoate ointment, Dinaid cream and other drugs treatment. Patients with significant itching can also take oral antihistamines such as cetirizine in combination. In addition, you need to pay attention to hand hygiene, avoid scratching, secondary infection. Avoid sharing personal items with others. When patients have a lot of small blisters on their hands, they should go to the dermatology department of the hospital immediately, and strictly follow the doctor’s instructions to carry out the corresponding treatment, not self-medication.