Hepatitis B four and five positive is hepatitis B five positive hepatitis B E antibody and hepatitis B core antibody positive. In the majority of hospital test reports in China, the fourth item in the normal order of the five hepatitis B items is hepatitis B E antibody, and the fifth item is hepatitis B core antibody, which represents a person who has been infected with the hepatitis B virus in the past and whose own immune system effectively cleared the hepatitis B virus, but did not produce protective surface antibodies, often the second item. It may represent a past infection with the hepatitis B virus long ago to clear the virus, or it can be a condition that occurs in patients in recovery.