The causes of waist pain and face swelling include chronic glomerulonephritis, nephrotic syndrome, renal insufficiency and so on. 1. Chronic glomerulonephritis: various causes can cause different lesions in the glomerulus, resulting in a series of clinical symptoms, in addition to back pain and swelling, accompanied by proteinuria, hematuria, hypertension and so on. 2. Nephrotic syndrome: Nephrotic syndrome is a clinical syndrome caused by various renal diseases, with large amount of proteinuria, hypoproteinemia, edema, hyperlipidemia as the main clinical manifestations, edema can be facial or generalized, and there can be back pain. 3. Renal Insufficiency: Renal insufficiency is the decline of glomerular filtration function and tubular concentration dysfunction caused by various renal diseases, and the clinical manifestations include hematuria, proteinuria, and hypertension in addition to waist pain and face swelling. There may be other reasons for the swelling, so it is recommended to improve the renal ultrasound and other systematic tests under the guidance of the doctor, so as to make a clear diagnosis and then carry out the corresponding treatment.