The preoperative preparation for pituitary tumor varies according to the surgical approach. For transcranial approach pituitary adenoma resection, the preoperative preparation mainly includes the following aspects: 1. Endocrine examination, including radioimmunological determination of various endocrine hormones in the pituitary gland, mainly to clarify which nature of pituitary tumor is involved. 2. 3. drug preparation, preoperative pituitary hypofunction should be supplemented with hormone three days before surgery. 4. intravenous antibiotics should be routinely administered 30 minutes before surgery, and the drug of choice should be one that can cross the blood-brain barrier, commonly used is ceftriaxone. 5. preoperative intravenous adrenal glucocorticoid should be given.