The difference between physiological and pathological is that physiological is a normal phenomenon, while pathological is an abnormal performance. 1. physiological: the general body in order to maintain its own homeostasis, there will be some compensatory behavior to make some indicators beyond the normal range, but the body does not have any disease, such as a large amount of hydration will appear physiological increase in urine, without any treatment, as long as no longer drink a lot of water urine will return to normal levels, this is physiological. 2. Pathological: This kind of reaction is mainly due to some parts of the body appear abnormal, which leads to some indicators beyond the normal range. For example, the increase in urine output is due to problems with the filtration function of the kidneys, and only after medication or surgical treatment will the urine output return to normal, which is pathologic. When judging the condition, we should pay attention to distinguish whether it is physiological or pathological, and we can ask the doctor for an interview.