Thyroid nodule drugs need to be based on the actual condition to determine, thyroid function is normal, asymptomatic generally do not need treatment. If combined with hyperthyroidism can use anti-thyroid drugs, combined with hypothyroidism can use levothyroxine sodium treatment, malignant thyroid nodule application of anti-tumor drugs combined with surgical treatment. For benign thyroid nodules, if the size of the nodule is small, the patient does not have obvious discomfort symptoms and the thyroid function is normal, no treatment can be taken and regular checkups can be done. Malignant thyroid nodules should be removed in time and treated with anti-tumor drugs. Thyroid nodules with abnormal thyroid function can be treated with corresponding drugs. Patients with hyperthyroidism can be treated with antithyroid drugs, such as propylthiouracil and methimazole. Patients with hypothyroidism can be treated with levothyroxine sodium to maintain normal thyroid hormone levels. It is recommended that patients with thyroid nodules go to the hospital in a timely manner to clarify the nature of the nodules and follow the doctor’s instructions for treatment to avoid delays.