Closed mouth medically known as whiteheads acne, can take general treatment, medication, physical therapy and other ways to improve. 1. General treatment: Patients with whiteheads and pimples need to pay attention to local hygiene and use mild cleansing products. Eat a light diet, avoiding the intake of high sugar, greasy and spicy food. Do not scratch the affected area to avoid secondary bacterial infection. 2. medication: patients with long whitehead acne on the brain, can follow the doctor’s instructions for external use of adapalene gel, tazarotene gel and other vitamin A cream, with the role of dissolving acne. You can also use topical azelaic acid, which can inhibit Propionibacterium acnes. 3. Physical therapy: Patients with whiteheads on the brain can use photodynamic therapy, which kills Propionibacterium acnes through photodynamic effect and facilitates the removal of acne. For those who have whiteheads, it is recommended to go to the hospital for standardized treatment. The medication should be used according to the doctor’s prescription.