Pimples are generally referred to as acne. After squeezing acne, you need to use iodophor or alcohol to disinfect it, and you can use mupirocin ointment, fusidic acid ointment and other medications to apply it topically so as not to lead to the spread of infection, and squeezing acne on your own is not generally recommended. Acne may be related to androgen levels, Propionibacterium acnes reproduction, dietary factors and so on. Patients are advised to keep the skin clean, eat a light diet, get enough sleep and avoid staying up late. Adapalene gel, tazarotene, benzoyl oxide, azelaic acid, isotretinoin and other medications can be used according to the condition of the acne; however, it is not recommended to squeeze and scratch acne by hand to avoid infection. If the acne is accidentally squeezed, the contents should be wiped clean with a sterile cotton swab and sterilized with iodophor or alcohol; and then applied topically with mupirocin ointment, fusidic acid ointment, etc. to prevent infection. If the squeezed acne appears red, swollen, enlarged, pain aggravated symptoms, suggesting that there may be infection, need to consult a doctor, if necessary, need to take oral amoxicillin, cefazolin sodium and other anti-inflammatory drugs, symptoms are serious need to be fed into the vein anti-inflammatory drug treatment. It is recommended that acne patients after the general life conditioning is ineffective, timely medical treatment, under the guidance of the doctor to choose the best treatment options, to avoid squeezing acne, or self-medication, in order to avoid delaying the condition.