Glomerulonephritis urine protein can turn negative, glomerulonephritis is divided into acute glomerulonephritis and chronic glomerulonephritis, acute glomerulonephritis no special treatment, after bed rest and symptomatic treatment of urinary protein can turn negative, chronic nephritis through active treatment, part of the patient’s urine protein can be negative. Chronic glomerulonephritis is to actively control blood pressure, reduce proteinuria, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers can be used to reduce proteinuria, protect renal function, part of the patient’s urinary protein turn negative, proteinuria heavier patients need to carry out a renal biopsy to clarify the type of pathology, for the type of pathology is less severe, hormone response sensitive patients, hormones and immunosuppressants after treatment Urine protein can turn negative, urine protein turn negative, renal function stabilization of patients with a better prognosis. However, chronic glomerulonephritis is a chronic progressive disease, until the uremia stage, it is necessary to renal replacement therapy, renal replacement therapy currently has hemodialysis and peritoneal dialysis, and actively treat various complications of uremia.