Waking up in the middle of the night with a sweaty chest may be a normal sweating phenomenon caused by heat, or it may be caused by heart failure, hyperthyroidism, tuberculosis and other diseases. 1. Normal physiological phenomenon: such as higher temperatures, the quilt cover too much, people will feel the heat, will be through sweating to disseminate heat, so that the body temperature is not too high; 2. Heart failure: due to the heart contraction and diastolic dysfunction, so that the heart blood supply is insufficient, venous blood stagnation caused by the heart circulation disorders. It mainly causes pulmonary stasis and so on, which can lead to dyspnea, fatigue, rales in the lungs and so on, and at the same time, it causes sympathetic excitation leading to the symptom of nocturnal sweating; 3. Hyperthyroidism: hyperthyroidism is a condition in which the thyroid gland synthesizes and releases too much thyroid hormone, causing hypermetabolism. Symptoms such as palpitations, fear of heat and sweating, insomnia, etc. can occur, and if left untreated for a long time, it can cause hyperthyroidism heart disease; 4. Tuberculosis: it is a chronic infectious disease caused by Mycobacterium tuberculosis, which may present symptoms such as low afternoon fever, night sweating, fatigue, chest pain, etc., and is more frequent in the elderly and diabetic patients. Chest sweating at night may also occur in other diseases. If it is accompanied by dyspnea, fatigue, chest pain and other discomforts, please go to the hospital in time to check and seek medical treatment according to the doctor’s advice.