Sore popliteal fossa after drinking beer consider gout, muscle strain, lumbar disc herniation. 1. Gout: drinking beer can easily cause uric acid excretion disorder, causing gout, popliteal soreness, some will be accompanied by redness and swelling, which can be relieved on its own, or you can take febuxostat. 2. Muscle strain: walking or squatting too much, easy to cause muscle strain around the knee joint, muscle pain, through hot compresses, massage symptoms can be reduced. 3. Lumbar disc herniation: nucleus pulposus herniation compression of nerves, drinking beer after tissue edema nerve compression aggravated, appearing to radiate to the popliteal fossa soreness, you can take the lumbar spine traction, acupuncture physiotherapy and other ways of treatment. Popliteal pain after drinking alcohol if through the rest did not get better need to promptly consult a doctor.