The main feature of the third generation IVF is the genetic diagnosis and screening of embryos. It mainly addresses carriers of genetic disorders, such as one parent having a balanced chromosomal translocation, such as a rosette or inversion, one parent being a carrier of a monogenic disorder or both parents being carriers of a monogenic disorder. The two main types of problems that are currently addressed are those of chromosomal disorders and those of monogenic disorders. The current success rate of the third generation IVF technology is about 40%. The indications for third-generation IVF technology are expanding as its technology continues to evolve. For example, custom embryo production, for example, the first child is thalassemia major and the second child is to provide umbilical cord blood stem cells to the first child for a cord blood stem cell transfer. When the second child has a third generation IVF technique, in addition to screening out the thalassemia gene, his HLA match should also be applicable to the first child match.