Symptoms of pulmonary regurgitation manifest as panic, chest tightness, shortness of breath, decreased activity tolerance, abdominal distension, loss of appetite, lower extremity edema, pleural effusion, abdominal effusion, and other manifestations of right heart failure. Severe pulmonary regurgitation can cause an increase in right ventricular load. Severe pulmonary regurgitation can lead to pulmonary hypertension, enlargement of the right ventricle, and an increase in pressure in the right atrium, which can lead to right heart failure in advanced stages. Further exacerbation of right heart failure can also cause total heart failure, which manifests as chest tightness, shortness of breath, inability to lie down, or even end-stage breathing. If a large amount of pulmonary regurgitation is found on cardiac ultrasound, it is important to go to the cardiology department for consultation and treatment, combined with the condition of the heart valves, whether there are any valve abnormalities caused by congenital abnormalities in valve development or acquired diseases, to further find out the cause of the large amount of pulmonary regurgitation.