There are many possible reasons for eating greasy food diarrhea, and depending on the cause, dietary adjustments combined with antidiarrheal, sedative, anti-infective, probiotic and other medications can be given. Eating greasy food diarrhea is not a specific clinical symptom of a certain disease, clinically there are many conditions that can lead to the emergence of this situation, the treatment method is also different, so when the patient appears to eat greasy food diarrhea symptoms first need to clarify the cause of the disease, in order to formulate the appropriate treatment plan. The cause of diarrhea from greasy food is irritable bowel syndrome (IBS), which is related to food intolerance, stress and the patient’s psychosomatic factors. Treatment needs to improve dietary habits, relieve mental stress, if necessary, can take antidiarrheal drugs and antidepressant treatment, commonly used are montelukast, amitriptyline and so on. Such as chronic gastroenteritis caused by patients eating greasy food diarrhea, mostly associated with Helicobacter pylori infection, intestinal flora disorders, etc., the treatment requires the application of anti-Helicobacter pylori drugs, intestinal probiotics and other drugs, commonly used amoxicillin, omeprazole, bismuth pectin, bifidobacteria and so on. If the symptoms continue to be unrelieved, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor to clarify the cause of the disease and targeted treatment, do not take medication on your own to avoid delaying the condition.