Very small blisters on the glans may be caused by genital herpes, pearly penile papules and so on. 1. Genital herpes: a common sexually transmitted disease caused by herpes simplex virus infection. Most people have no obvious symptoms, and some people may show herpes, localized vesicles and ulcers on the genitals or perineum, which may be accompanied by pain, abnormal local sensation, fever and other symptoms. It can be manifested as very small blisters on the glans. 2. pearly penile papules: it is a common skin disease, occurring in the male penile coronal groove, mostly seen in the circumcision and masturbation habits of young people. The main manifestation of translucent pimples visible to the naked eye, the number of large, slow-growing, no itching and other symptoms. It can also be manifested as very small blisters on the glans. There are many other causes of very small blisters on the glans, which should be emphasized, timely consultation and examination, identify the cause of the disease, and early treatment.