Oil grains in the pores are usually closed acne, which can be helped to be removed by medication, medical aesthetic treatments, and life adjustments. 1. Medication: If the patient’s acne is mild, adapalene gel, benzoyl peroxide gel, salicylic acid ointment and other ointments can be applied locally to help reduce inflammation and remove it. If the acne is more serious or larger in size, it is necessary to take minocycline, doxycycline, isotretinoin and other medications to help relieve inflammation and inhibit sebum secretion, thus improving the oil particles. 2. Medical aesthetic treatment: For patients with more obvious acne and greater impact on their appearance, photorejuvenation, fruit acid skin resurfacing and other medical aesthetic treatments can be used to help improve the excessive oil secretion of the face and closed pimples, so as to improve the quality of the skin to a certain extent. 3. Lifestyle adjustment: In addition to the above treatments, patients should pay attention to adjust their lifestyle to help effectively improve closed acne. For example, we should pay attention to light diet, avoid spicy and stimulating food, quit smoking and drinking; morning and evening facial cleaning, remove excessive oil secretion, strengthen the hydration and moisturizing work; maintain sufficient sleep and good mood. It should be noted that the above drugs need to be carried out under the guidance of a physician to avoid the occurrence of adverse reactions. It is recommended that patients go to the hospital in a timely manner, and follow the doctor’s instructions for treatment.