The best time to drink lemon enzyme is usually after lunch and 30 minutes after dinner. It is not easy to take lemon enzyme on an empty stomach because it is rich in citric acid, which is an acid and can cause great stimulation to the gastric mucosa. Long-term use of lemon enzyme can cause gastric mucosa erosion, acid reflux, nausea, vomiting, even acid reflux, heartburn, and bile reflux gastritis at night. If you drink lemon enzyme on an empty stomach or at bedtime for a long time, it will also cause increased peristalsis in the gastrointestinal tract, resulting in unstable sleep, especially in the early hours of the morning when the number of bowel movements will increase and obvious variation will occur. If lemon enzyme is taken for a long time, it will also promote permeability diarrhea of the gastrointestinal tract and cause nausea, vomiting, acid reflux, heartburn and other undesirable conditions in the evening. Therefore, the best time to drink lemon enzyme is 30 minutes after lunch and 30 minutes after dinner.