Gastric sinus xanthoma is usually not harmful and is a benign lesion. Smaller xanthomas can be temporarily observed; however, gastric sinus xanthoma may lead to gastric lesions or even malignant lesions, so larger gastric xanthomas are recommended to be removed under gastroscopy as early as possible. 1. Xanthomas are yellowish-white tumor-like plaques formed in the gastric mucosa, which are benign lesions. It is a benign lesion. It is mainly caused by chronic gastritis, which leads to the local destruction of gastric mucosa, and the residual confetti is swallowed up and gathered into the foam cell nest structure, which then forms xanthomas. Usually occurs in the gastric sinus, mostly manifested as round, single, yellowish-white, plaque, different sizes, etc., can appear acid reflux, nausea and other symptoms. 2. If the tumor of xanthoma is relatively large, gastroscopic resection can be chosen, and pathological examination can be carried out after the operation to clarify whether there is cancer or not. If the patient is diagnosed with gastric sinus xanthomas, it is recommended to go to the regular hospital in time, under the guidance of the doctor to carry out targeted treatment, in order to reduce the adverse effects of the disease.