The effects of spleen removal on the body include: susceptibility to immunity decline, susceptibility to thrombotic diseases, and so on. 1. Decreased immunity: the spleen is the immune organ in the body, when the spleen is removed for various reasons, there will be a short-term decrease in immunity, and the risk of various infections will be elevated, but this situation will not last forever, and there will be other organs to make up for the immunity of the spleen. 2. Prone to thrombotic diseases: after the spleen is removed, it will not be able to destroy the blood cells through the spleen, and the blood cells in the body will increase, especially the platelets will increase significantly, which will be very prone to thrombotic diseases, and anticoagulant drugs, such as aspirin, should be given for treatment. After splenectomy, it is important to have regular checkups in the hospital and follow the doctor’s instructions for treatment.