How is arterial duct failure with pulmonary hypertension treated?

       Pulmonary hypertension is one of the common and serious complications of left-to-right shunt precordial disease, and a proportion of patients are lost to treatment as a result. The most critical factor in the treatment of arteriovenous insufficiency complicated by pulmonary hypertension is to distinguish between powered or resistance pulmonary hypertension.  The former is due to increased pulmonary blood flow and aortic collateral pressure conduction and is reversible; the latter is due to vascular remodeling and wall thickening due to constriction and spasm of small pulmonary vessels under the effect of long-term hypertension, which gradually increases vascular resistance and is therefore irreversible.  Clinically, pulmonary hypertension is often the presence of both. Especially in patients with severe pulmonary hypertension, the vascular lesion is in a critical state and it is difficult to accurately determine its nature by one indicator or one test.  Surgical procedures have not been the traditional method of treating unclosed arterial ducts. However, surgery is traumatic and the chance of complications is relatively high. Especially in patients with severe pulmonary hypertension, it is difficult to grasp the nature of the pulmonary vascular lesion.  In recent years, with the development of the Amplatzer blocker, interventional blocking began to be widely used in the treatment of unclosed arterial ducts. the Amplatzer blocker has the characteristics of simple operation, safety, wide indications, and few complications, especially for patients with severe pulmonary hypertension, it is clinically difficult to determine dynamic pulmonary hypertension or resistance pulmonary hypertension, and the blocking test can It is very good to identify the two different nature of pulmonary hypertension.  In our experience, as long as the indications are properly grasped, the chance of serious complications of interventional occlusion therapy is extremely low, and there is no significant difference between the therapeutic effect of interventional occlusion and surgical ligation.  Since resistance pulmonary hypertension will have serious consequences once the arterial catheter flow is blocked, which is difficult for surgery to identify during surgery, the indications for surgery should be more strictly grasped in patients with pulmonary hypertension, which also makes it possible for some patients to lose treatment opportunities.  In contrast, interventional treatment can be performed for blocking test, and after trial blocking, patients are observed to have no drop or rise in pulmonary artery pressure, drop in aortic pressure, and drop in oxygen saturation, which indicates that pulmonary hypertension is resistance, and the blocker can be retrieved quickly, thus greatly reducing the chance of PH crisis and acute right heart attenuation, so the indications can be relaxed appropriately.  However, interventional blocking treatment has its own limitations, for the larger internal diameter of the unclosed artery guide after blocking easy to appear residual shunt and cause hemolysis, and the blocker is easy to dislocate or even fall off, therefore, the diameter of the unclosed arterial catheter greater than 15mm or surgical operation is appropriate.