People with bile reflux who lose weight need to improve their dietary structure, take oral medication to inhibit bile reflux and improve digestion. 1. Improve the diet structure: on the basis of adequate nutrition, usually pay attention to avoid eating hard, cold, spicy and stimulating food, do not overeat, pay attention to small meals, which is conducive to the absorption of nutrients. At the same time, we should also pay attention not to drink alcohol, to avoid damage to the gastric mucosa. 2. Oral medication to inhibit bile reflux: For patients with bile reflux, it is necessary to take oral medication to inhibit reflux and protect the gastric mucosa under the guidance of a doctor, such as omeprazole enteric-coated capsules, colloidal bismuth pectin capsules, domperidone and so on for treatment, which is conducive to the reduction of bile reflux and the protection of the gastric mucosa. For patients with bile reflux, it is recommended to consult the gastroenterology department of regular hospitals, do not self-medicate and delay diagnosis and treatment.