Bone imaging is one of the most commonly used imaging examinations in nuclear medicine, accounting for about 1/3 of nuclear medicine imaging examinations, which is a technique of injecting osteophilic radioactive drugs into the body through a vein and then imaging the whole body through special instruments and equipment. It can show the morphology of the whole body bones more clearly, and it can reflect the blood supply and metabolism of bones, so it is of great value for the diagnosis of various bone diseases and the observation of treatment effects. The most important clinical application is the early detection of bone metastases, and it is an essential test for the pre-treatment staging of some malignant tumors that are prone to early bone metastases, such as prostate cancer, breast cancer and lung cancer, and it is also a crucial test for what kind of treatment to take.