If the itching is more intense at night after the baby develops eczema, it may be related to the following aspects: First, the vagus nerve is more excited at night, resulting in stronger mast cell sensitivity and the release of inflammatory mediators from mast cells, causing vasodilation and increased vascular permeability, thus aggravating the itching. Second, at night the baby is in a state of imminent sleep, there is not much to distract, the slight itching symptoms will be magnified, scratching will lead to more pronounced itching. Third, the baby sleeps at night in the sheets, covers wrapped in a large number of mites in the sheets, covers and pillows, mites are one of the common allergens that cause eczema to worsen, the body is prone to allergic reactions after contact with such allergens, resulting in more pronounced itching.