Hand shaking may be a symptom of Parkinson’s disease, hyperthyroidism, hypocalcemia, hepatic encephalopathy and other diseases, but it is not a so-called precursor. 1. Parkinson’s: elderly patients with resting tremor, thumb and forefinger flexion in the “pill-like”, dyskinesia, bradykinesia, balance disorders and other symptoms are likely to be Parkinson’s disease symptoms, the disease and genetic, neurodegenerative factors such as the nigrostriatal dopaminergic neuron apoptosis related. 2. Hyperthyroidism: hand shaking accompanied by thinness, panic, excessive sweating, irritability, insomnia and other symptoms are likely to be symptoms of hyperthyroidism. 3. Hypocalcemia: serum calcium ions have the effect of antagonizing sodium ions and reducing nerve excitability, and increased nerve excitability can cause muscle contraction and spasm, so the hands will shake. 4. Hepatic encephalopathy: patients with liver cirrhosis and liver cancer may have symptoms of hepatic encephalopathy such as mental abnormality and shaking hands (flutter-like tremor). Shaking hands may be a symptom of many diseases, and you need to consult a doctor for a clear diagnosis.