There are many reasons why you keep coughing in your sleep, such as cough variant asthma, cardiac insufficiency, gastroesophageal reflux disease and so on. 1. Cough variant asthma: it is a special type of asthma, which is mainly characterized by irritating dry cough, mostly occurring at night and in the early hours of the morning, without obvious symptoms such as wheezing and shortness of breath. It can be treated with inhaled glucocorticosteroids (e.g. budesonide) and bronchodilators (e.g. salbutamol) under doctor’s guidance. 2. Cardiac insufficiency: some patients with chronic cardiac insufficiency, lying down at night, there will be an increase in the volume of return blood, increased cardiac load, aggravated pulmonary stasis, causing coughing, accompanied by dyspnea, coughing up pink foamy sputum, you can take the sitting position, the symptom can be alleviated, but it is necessary to consult a doctor in a timely manner. 3. Gastroesophageal Reflux Disease (GERD): Sleeping and coughing may be caused by acid reflux that irritates the throat. You can consider giving drugs to inhibit gastric acid, promote gastrointestinal peristalsis, and protect the gastric mucosa to improve the symptoms, and you can use lansoprazole, ranitidine, domperidone, and aluminum hydroxide under the guidance of a doctor. The above medicines are for reference only, the specific dosage should follow the doctor’s instructions. The symptoms of sleeping and coughing, it is recommended that patients go to the hospital in time, follow the doctor’s instructions for further examination, to clarify the cause, under the guidance of the doctor for targeted treatment or treatment.