After chemotherapy for advanced systemic metastasis of lung adenocarcinoma, patient’s symptoms can be improved, but the disease cannot be completely relieved. Chemotherapy for advanced systemic metastasis of lung adenocarcinoma can inhibit tumor growth and destroy tumor cells, which can help to shrink the primary foci and metastatic foci of the tumor and reduce the tumor load of the body, thus alleviating the pain, fatigue and other discomforts brought by the tumor, and bringing initial relief to the patient’s symptoms. Patients with advanced systemic metastasis of lung adenocarcinoma can not be completely improved by chemotherapy alone, and chemotherapy can only control the growth rate of the tumor to a certain extent and alleviate some of the symptoms of the patients, but can not reverse the condition of the patients with tumors. It is necessary to pay attention to. Patients with advanced systemic metastasis of lung adenocarcinoma should also establish confidence in treatment and go to the hospital in time, through radiotherapy, chemotherapy, targeted therapy and other comprehensive treatment measures are expected to prolong the survival period of patients.