The main medications commonly used for gout attacks are non-steroidal anti-inflammatory drugs (NSAIDs), colchicine, glucocorticoids, and other symptomatic medications.
1. Non-steroidal anti-inflammatory drugs: such as indomethacin, diclofenac sodium and so on. These drugs contain steroids in their chemical structure, which can relieve pain and swelling by inhibiting the synthesis of prostaglandins. Therefore, they can be used to relieve joint pain during gout attacks, etc. Long-term use of the drugs may cause gastritis, gastric ulcers and other adverse reactions. Gastrointestinal bleeding, renal insufficiency and other patients are contraindicated.
2. Colchicine: It can be used to relieve joint pain and swelling during acute attack of gout by reducing the activity of white blood cells and phagocytosis. Prolonged use will cause diarrhea, vomiting and other gastrointestinal adverse reactions, and should be avoided with allopurinol when using this drug. Bone marrow hypoplasia, hepatic and renal insufficiency are contraindicated.
3. Glucocorticoids: such as methylprednisolone, prednisone acetate tablets. They can inhibit the immune response and thus reduce the symptoms of acute gout attack. Long-term use may lead to substance metabolism disorders, neurological, skeletal and other systemic adverse reactions. Contraindicated for women during pregnancy and lactation.
4. Other symptomatic treatment drugs: gout remission must also use uric acid-lowering drugs such as allopurinol, febuxostat and so on.
Note that patients should be under the guidance of a doctor to use drugs, different patients with individual differences in the drug program, not blindly self-medication. It is recommended that gout patients go to the rheumatology and immunology department in a timely manner, under the guidance of the doctor for standardized treatment, and regular follow-up.