There is no such thing as a quick recovery medicine for weakness in both legs, it may be caused by physiological factors such as overwork, or it may be caused by pathologic factors such as lumbar spine disease, hypokalemia, osteoporosis, upper respiratory tract infections, etc. Targeted treatment can be given for the cause with oral non-steroidal, nutritive nerve, electrolyte supplementation and other drugs. 1. Excessive fatigue: Excessive fatigue caused by excessive activity or prolonged exercise, lack of physical strength, or accumulation of lactic acid in the body may cause weakness or even soreness of the legs, which can be restored to normal after proper rest. 2. Lumbar spine disease: patients with lumbar disc herniation, due to the herniated intervertebral disc compression of the nerve root can cause weakness of the legs, as well as lower limbs of the radiating pain and numbness, etc., can be under the guidance of the doctor orally Celecoxib, Loxoprofen sodium anti-inflammatory analgesics, oral methylcobalamin, Vitamin B1 and other nutritive nerve medication. 3. Hypokalemia: Hypokalemia can be manifested as muscle weakness, weakness of legs, etc. More fresh vegetables and meat rich in potassium can be consumed, and potassium citrate tablets and other medications can be taken orally under the guidance of doctor. 4. Osteoporosis: Osteoporosis can lead to weakness of legs due to the decrease of blood calcium and the disturbance of electrolyte level in the body, which can be treated with oral medication such as calcium carbonate or calcium citrate as prescribed by the doctor. 5. Upper respiratory tract infection: upper respiratory tract infection caused by cold or decreased resistance, can be caused by fever leading to excessive energy consumption, resulting in weakness and weakness of the legs, can be prescribed oral antiviral drugs or antibiotics, etc. for treatment. When the patient’s legs are weak, you need to consult a doctor in time to clarify the condition and then actively carry out targeted treatment.