The generic name of Nosyntho is Sacubitril Valsartan Sodium Tablets, and the dosage is 100-400mg per day.The specific use of the drug should follow the instructions of the physician. Sacubitril valsartan sodium tablets can be used for the treatment of chronic heart failure and essential hypertension, with specifications ranging from 50mg, 100mg and 200mg per tablet. The dosage for the treatment of chronic heart failure is 50-100mg each time, twice a day; for the treatment of hypertension, 200-400mg can be used once a day according to the condition. In addition, the dosage should be reduced for those with liver and kidney function impairment, and the specific treatment plan should be determined by the physician according to the patient’s condition. This drug may cause edema, hypotension, renal damage, hyperkalemia and other adverse reactions, and is contraindicated in allergic patients, patients with hereditary or idiopathic angioedema. Blood pressure should be monitored and observed for any discomfort after use of the drug, and the drug should be discontinued and medical attention should be sought promptly if any adverse reaction occurs after use of the drug.