If the surface antigen of hepatitis B is greater than 500 ng/ml, the first step is to further look at the other items in the hepatitis B triple system to see if the patient is a minor or major triple-positive. If the patient is a small triple-positive patient, there is no viral replication, and if the liver function is normal, you can continue to observe. If there is a combination of viral replication and elevated liver function glutathione transaminase, antiviral treatment should be actively considered. You can choose oral antiviral drugs, such as entecavir and tenofovir, or you can actively consider injecting interferon for six months to a year. After aggressive antiviral treatment, most patients will have their viral replication under control and the patient’s hepatitis B will be controlled. Patients should be careful not to drink alcohol, not to stay up late, not to strain, and to pay attention to the diet, not to overeat.