Under normal circumstances, antihypertensive drugs can be combined with probiotics, and drug interactions between the two types of drugs generally do not occur. The mechanism of action of antihypertensive drugs includes lowering vascular resistance, decreasing vasoconstriction, decreasing cardiac contraction, increasing vasodilatation, etc. They are absorbed in the gastrointestinal tract, play a role in many parts of the body such as blood vessels, muscles, nerves, etc., and finally metabolized by organs such as the liver and kidneys. Probiotics can replenish probiotics in the intestinal tract and improve diarrhea and indigestion caused by intestinal flora imbalance. Directly supplemented intestinal flora after the retention of the intestinal tract, the supplemented probiotics and the original intestinal presence of beneficial bacteria, and will not interact with antihypertensive drugs, and will not affect their digestion, absorption, functioning and metabolism. Combined with the mechanism of action of antihypertensive drugs and probiotics, under normal circumstances, the two types of drugs will not interact with each other and will not affect the efficacy of the drug, so the two can be taken together. The use of drugs need to be under the guidance of a professional doctor, it is recommended to consult a doctor, standardized treatment.