The 13-valent vaccine refers to the 13-valent pneumonia vaccine, after playing the arm swollen with the vaccine reaction, local infection or improper operation, etc., should be timely to the general treatment, medication and other ways to intervene. 1. Vaccine reaction: after vaccination, some children may have a low fever, skin rash and redness and swelling at the vaccination site, which is a normal reaction to vaccination, and there is no need to worry about it, only need to strengthen the observation, and the symptoms will basically disappear in two or three days. 2. Localized infection: after vaccination without good hygiene, leading to infection of pathogens at the inoculation site, and then local dermatitis, can also cause this symptom. For this kind of disease, you can apply erythromycin ointment and other drugs under the guidance of the doctor for treatment. After the use of drugs, nausea, drug fever and other adverse reactions, can promptly seek medical treatment. 3. Improper operation: improper operation during injection, resulting in local damage, can also lead to local redness and swelling. In this case, observation is also the main focus, but also can take the local ice packs to deal with. If any of the above adverse reactions occur after vaccination, you can consult a doctor in time and follow the doctor’s instructions.