A 50-year-old man’s difficulty in urinating may be caused by prostate hyperplasia, urethral stenosis, prostatitis, etc., and need to take medication and surgical treatment for the cause of the disease. 1. Prostatic hyperplasia: 50-year-old men with prostatic hyperplasia will have difficulty urinating, patients can use doxazosin, terazosin and other alpha-blockers under the guidance of the doctor, as well as M-receptor antagonists, such as tolterodine, solinacin and so on. For patients with moderate to severe prostatic hyperplasia, they also need to be treated with transurethral resection of the prostate and transurethral prostatectomy. 2. urethral stenosis: 50-year-old man urinary difficulties may also be caused by urethral stenosis, for the emergence of simple navicular fossa segment or urethral stenosis of patients, can take urethral dilatation, urethral epithelial incision treatment. If the patient has a short penis urethral stenosis, you need to take the penis flap urethroplasty, penis flap combined with oral mucosa urethroplasty treatment. 3. Prostatitis: If the patient has acute bacterial prostatitis, you can follow the doctor’s instructions with cefixime, amoxicillin and other antibiotics. For patients with chronic prostatitis, it is necessary to follow the doctor’s instructions with levofloxacin, azithromycin and other antibiotics. Acute bacterial prostatitis patients with abscesses need to take incision and drainage, prostate puncture pus drainage. If the patient develops chronic prostatitis, then it can take the transurethral electrolysis prostatectomy treatment. The 50-year-old man urinary difficulties may also be caused by prostate cancer, it is recommended that the patient should consult a doctor in a timely manner, in accordance with the doctor’s instructions.