Taking misoprostol stomach will have some pain, most people can tolerate, some pain sensitive people pain can be relatively intense. Misoprostol has a softening of the cervix, promote uterine contraction and other effects, clinically often paired with mifepristone, used in 49 days of pregnancy medication abortion, first take mifepristone, then eat misoprostol, at this time the uterus contraction, to promote the discharge of pregnancy in the uterine cavity, the process of the patient’s stomach will be a certain degree of pain, the majority of people can tolerate, some of the pain sensitivity of the pain can be relatively intense. The common adverse reactions of misoprostol are nausea, vomiting, dizziness, etc.; it should not be applied to those who suffer from adrenal gland diseases; it should not be applied to those who have carrier pregnancy and ectopic pregnancy; it should not be applied to those who suffer from glaucoma, asthma and other diseases. If the patient has the need to use the drug, must have a professional physician from the side of the guidance, not blindly take, so as not to lead to adverse consequences.