Hemolytic anemia refers to a type of anemic disease caused by the destruction of red blood cells, and the causes are commonly found in the following: a. Red blood cell self factors: 1. Red blood cell membrane abnormalities: can lead to hereditary spherocytosis; 2. Red blood cell enzyme deficiency: such as glucose-6-phosphate dehydrogenase deficiency; 3. Hemoglobin abnormalities: such as porphyria; 4. Bead protein synthesis disorders: such as thalassemia. Second, factors other than red blood cells: 1, immune diseases: such as autoimmune hemolytic anemia, which can be divided into warm antibody type, cold antibody type, etc.; 2, vascular diseases: such as microangiopathic hemolysis, commonly seen in thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, disseminated intravascular coagulation, and heart valve disease, especially in patients with prosthetic heart valves, hemolytic anemia can also occur; 3, other diseases : including malaria, snake bites, massive burns, and nitrite poisoning, all of which can lead to hemolytic anemia.