Liver tissue elasticity grade F4 usually means that the liver tissue elasticity is very poor and the degree of liver fibrosis is very high, which requires timely medical treatment once discovered. Liver tissue elasticity test is often used in cirrhosis disease, which can effectively check the transient elastic fiber of liver and then analyze and judge the degree of liver fibrosis, and the test result can be classified into F0~F4. If the elasticity of liver tissue reaches F4 grade, it means that the degree of cirrhosis has been reached. However, liver tissue elasticity examination alone cannot confirm the diagnosis of cirrhosis, at this time, it is necessary to combine with the patient’s symptoms, signs, biochemical and imaging examinations to comprehensively determine the degree of cirrhosis of the patient.