High jaundice in babies requires symptomatic treatment according to the nature of jaundice. It can be divided into physiological and pathological jaundice, which can be treated with regular review or blue light irradiation and medication. Generally speaking, high jaundice in babies is divided into physiological jaundice and pathological jaundice. Physiological jaundice in newborns is a normal phenomenon, which can subside naturally in 1~2 weeks after birth, so close observation and regular checkup are recommended. If the baby’s jaundice appears very early or the degree is more serious, full-term babies >12.9mg/dl, preterm babies >15mg/dl, it is called pathological jaundice. Pathologic jaundice is most commonly treated with blue light irradiation, which promotes the excretion of unconjugated bilirubin. In case of hemolytic jaundice, immunoglobulin is mainly applied to reduce serum bilirubin concentration. If the jaundice is caused by infection, it needs to be actively combined with anti-infection drugs. If jaundice is not treated in time, it can induce bilirubin encephalopathy, causing neurological damage. Parents are advised to consult a pediatrician if they find their baby with jaundice, and to treat it under the guidance of the pediatrician, so as not to delay the condition.