Parkinson’s disease treatment requires different medication regimens according to different populations, as follows: 1, patients younger than 65 years old without cognitive impairment are usually preferred to dopamine agonists or monoamine oxidase inhibitors, dopamine agonists, namely piribedil and senflora drugs, which have a neuroprotective effect and can slow the progression of the disease, so they should be preferred for younger patients. Monoamine oxidase inhibitors are selagiline, also has a certain role in protecting nerve cells to delay the progression of the disease, so also as the first choice; 2, patients over 65 years of age or with cognitive decline, preferred compound levodopa preparations, is a drug for the pathogenesis of Parkinson’s disease, so artificial supplementation of levodopa, the effect is very obvious, more patients who have taken this drug have felt, but patients need to be reminded that this However, patients should be reminded that this drug cannot be easily increased without authorization, because the dose of this drug will gradually increase as Parkinson’s disease gradually progresses. Therefore, the adjustment of levodopa dosage should be guided by a specialist, so patients should be advised not to easily adjust the levodopa dosage by themselves.