Thickened toenails are first determined what the cause is. If the nail is caused by malnutrition, you can supplement some vitamins and take medications such as gold vita to improve some of the symptoms of the nail. If it is a fungus caused by gray nails, can also be manifested as thickening, yellowish color, dull, rough surface, under the nail debris and other symptoms, such as this situation should choose antifungal drugs for treatment. Generally choose terbinafine hydrochloride tablets or itraconazole capsules, for 3-4 months as a course of antifungal treatment. During and before treatment, liver function tests are required, and only if the liver function is normal can this drug treatment be continued orally. Once the liver enzymes become abnormal, it should be stopped immediately. Because the effect of this medication on the liver is quite strong, it is important to ensure that you are in good health before proceeding with the treatment.