The most common cause of soreness in the upper hamstrings is spinal problems. Degeneration of the spine with age often causes spinal problems, including spinal stenosis, herniated discs, spondylolisthesis, and small joint disorders in the lumbar spine, and a series of problems may lead to inflammatory stimulation of the nerve roots of the spine by compression, resulting in pain in the sciatic nerve area. The pain increases when walking too much or sitting for a long time and can be relieved after activity. Another cause of soreness in the upper hamstrings is pear-shaped muscle syndrome, in which the sciatic nerve exits from the pear-shaped muscle, and if various causes lead to inflammation or swelling of the sciatic nerve, it can also cause sciatica, which requires careful clinical differentiation. In a few cases patients can also cause soreness of the tendons in the legs because of prolonged walking. Certain elderly male patients who have been smoking for a long time often have poor blood flow due to vaso-occlusive vasculitis in the lower extremities, or diabetic patients with poor peripheral blood flow can have sore legs after a slightly prolonged walk, and patients need to visit a vascular surgery clinic for identification.