Herpes zoster is a common inflammatory reaction of the epidermis caused by infection with the varicella-zoster virus. In clinical practice, herpes zoster often invades the sensory nerves, resulting in localized nerve inflammation and necrosis, which leads to severe neuralgia. However, some patients with severe herpes zoster or who are older or have poorer immune resistance may have residual herpes zoster neuralgia. Patients with shingles also experience significant and severe neuralgia after scabbing, which is actually a relatively common clinical occurrence. Especially in the elderly, some patients can have neuralgia long after the herpes zoster has completely healed. In this case, the patient can usually be relieved orally by some painkillers such as diclofenac. The patient can also choose to be treated with gabapentin or pregabalin, as well as some laser surgery.