Ehrlich’s syndrome would be known as Dreh-Ehrlich syndrome, which typically has symptoms such as abdominal pain and diarrhea. Dreh-Eyre syndrome, also known as gastrinoma, is a gastroenteropancreatic neuroendocrine tumor usually characterized by refractory, recurrent or atypical sites of peptic ulcers as well as high gastric acid secretion. Zuo-Ai syndrome often presents clinically with clinical symptoms such as abdominal pain and diarrhea, often with intractable peptic ulcers, and frequent complications such as perforation, bleeding, or obstruction, which can even be life-threatening. However, there are few obvious symptoms in the early stage, and a large amount of gastric acid secretion and the above manifestations can only appear in the late stage. It is recommended that patients in need of treatment should seek timely medical treatment under the guidance of a doctor.