Fever when taking antipyretic drugs will not keep sweating, fever when oral non-steroidal antipyretic drugs can make the body sweating, such as diclofenac sodium extended-release tablets, ibuprofen suspension and other drugs, through the evaporation of sweat to make heat distribution, so that the body temperature gradually drop back to normal, the use of medication for half an hour to an hour or so will begin to sweat, the size of the sweating and the speed of the fever vary from person to person, the majority of patients with the temperature gradually returned to normal after sweating more can gradually stop, will not keep sweating. Most patients’ body temperatures gradually return to normal and sweating can be stopped gradually, not non-stop sweating. But clinically there are a few patients such as the old and weak, infants and young children, there may still be persistent sweating after the fever subsides, such patients should pay attention to timely supplementation of fluids and replacement of soaked clothing. Therefore, when using antipyretic drugs for fever, we should pay attention to the age and condition of the patient, pay attention to the dosage and replenish the fluids in time to avoid the patient from sweating a lot, which may cause the patient to fall into a state of collapse or shock.